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Ultragenyx Pharmaceutical

15.22

+0.47003.19%

Post-market: 15.05-0.1700-1.12%19:54 EDT

Volume:3.88M

Turnover:58.72M

Market Cap:1.50B

PE:-2.61

High:15.28

Open:14.90

Low:14.67

Close:14.75

52wk High:39.89

52wk Low:12.73

Shares:98.32M

Float Shares:80.72M

Volume Ratio:0.82

T/O Rate:4.81%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-5.8279

EPS(LYR):-5.8316

ROE:-608.47%

ROA:-24.22%

PB:-5.14

PE(LYR):-2.61

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Overview Company News Filings

Ultragenyx Stock Sinks 47% on Drug Trial Failure. Why Wall Street Isn't Giving up Yet.

U.S. Stocks on the MOVE-Snowflake, Ultragenyx Pharmaceutical, Broadcom

Top Premarket Decliners

MT Newswires Live

Wedbush Adjusts Price Target on Ultragenyx Pharmaceutical to $23 From $30, Maintains Neutral Rating

MT Newswires Live

Canaccord Genuity Sticks to Its Buy Rating for Ultragenyx Pharmaceutical (RARE)

Ultragenyx price target lowered to $37 from $83 at Canaccord

Ultragenyx price target lowered to $25 from $50 at H.C. Wainwright

Stocks to Watch: Snowflake, Broadcom, HPE, Ultragenyx

Ultragenyx Pharma is Maintained at Overweight by Cantor Fitzgerald

Ultragenyx Pharmaceutical Shares Crash 45% After Angelman Syndrome Drug Trial Disappoints

Ultragenyx Pharmaceutical Inc. : Baird Cuts to Neutral Rating; Cuts Target Price to $16 from $40

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc. : TD Cowen Cuts Target Price to $18 from $49

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc. : Canaccord Genuity Cuts Target Price to $37 from $83

THOMSON REUTERS

Ultragenyx downgraded to In Line from Outperform at Evercore ISI

Evercore ISI downgrades Ultragenyx Pharmaceutical (RARE) to a Hold

Ultragenyx downgraded to Market Perform from Outperform at William Blair

William Blair downgrades Ultragenyx Pharmaceutical (RARE) to a Hold

Ultragenyx Says Phase 3 Study on Rare Neurogenetic Disorder Missed Primary, Secondary Endpoints; Shares Fall After-Hours

MT Newswires Live

Ultragenyx Pharmaceutical to Cut Costs After Drug Trial Misses Endpoints

Ultragenyx's Rare Disease Drug Fails in Late-Stage Trial

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Premarket Decliners","url":"https://stock-news.laohu8.com/highlight/detail?id=2664797048","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664797048?lang=en_us&edition=fundamental","pubTime":"2026-09-03 19:37","pubTimestamp":1788435423,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical  shares were down 50% in premarket activity Thursday after the company said overnight that its phase 3 Aspire study of apazunersen in Angelman syndrome - a rare neurogenetic disorder - failed to meet the primary endpoint and a key secondary endpoint.Research Alliance  stock was 21% lower, extending the 3.7% fall in the previous session.Victoria's Secret  shares were down 16% following its fiscal Q2 results.Methode Electronics  stock was 14% lower after the company posted a wider-than-expected fiscal Q1 adjusted loss late Wednesday.Advasa  shares were down 12% after a more than 53% fall at the previous close when the company said it added USDC  payments to its Visa card.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["MEI.AU","RARE","ADBT","VSXY","BK4023","BK4094","BK4139","RACC","MEI","BK7095","BK4145"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664879849","title":"Wedbush Adjusts Price Target on Ultragenyx Pharmaceutical to $23 From $30, Maintains Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2664879849","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664879849?lang=en_us&edition=fundamental","pubTime":"2026-09-03 19:06","pubTimestamp":1788433581,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical (RARE) has an average rating of overweight and mean price target of $33.95, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic resear","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664876714","title":"Canaccord Genuity Sticks to Its Buy Rating for Ultragenyx Pharmaceutical (RARE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2664876714","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664876714?lang=en_us&edition=fundamental","pubTime":"2026-09-03 18:56","pubTimestamp":1788432980,"startTime":"0","endTime":"0","summary":"Canaccord Genuity analyst Whitney Ijem maintained a Buy rating on Ultragenyx Pharmaceutical today and set a price target of $37.00. Ijem covers the...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/canaccord-genuity-sticks-to-its-buy-rating-for-ultragenyx-pharmaceutical-rare-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/canaccord-genuity-sticks-to-its-buy-rating-for-ultragenyx-pharmaceutical-rare-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664764008","title":"Ultragenyx price target lowered to $37 from $83 at Canaccord","url":"https://stock-news.laohu8.com/highlight/detail?id=2664764008","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664764008?lang=en_us&edition=fundamental","pubTime":"2026-09-03 18:55","pubTimestamp":1788432910,"startTime":"0","endTime":"0","summary":"Canaccord lowered the firm’s price target on Ultragenyx (RARE) to $37 from $83 and keeps a Buy rating on the shares. The firm updated its model aft...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-37-from-83-at-canaccord-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-37-from-83-at-canaccord-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664087542","title":"Ultragenyx price target lowered to $25 from $50 at H.C. 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Wainwright analyst Raghuram Selvaraju lowered the firm’s price target on Ultragenyx (RARE) to $25 from $50 and keeps a Buy rating on the share...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-25-from-50-at-h-c-wainwright-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-25-from-50-at-h-c-wainwright-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664878017","title":"Stocks to Watch: Snowflake, Broadcom, HPE, Ultragenyx","url":"https://stock-news.laohu8.com/highlight/detail?id=2664878017","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664878017?lang=en_us&edition=fundamental","pubTime":"2026-09-03 17:30","pubTimestamp":1788427800,"startTime":"0","endTime":"0","summary":"Snowflake : The cloud-storage company reported a narrower quarterly loss, saying AI drove its business. Its stock surged more than 20% ahead of the bell.Broadcom : The company was bullish about demand for its custom chips over the next two years; shares slipped premarket.Hewlett Packard Enterprise : The company's results beat analyst expectations, helped by AI demand. It also lifted its long-term goals; alas, this wasn't enough to boost its shares, which fell around 4% ahead of the bell.Impala Platinum : Higher precious-metal prices gave the South African miner's earnings a boost; its shares climbed.Ultragenyx Pharmaceutical : The pharma company said a drug in its pipeline failed to meet its primary endpoint in a late-stage trial; its stock plunged about 45% ahead of the 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Pharma is Maintained at Overweight by Cantor Fitzgerald","url":"https://stock-news.laohu8.com/highlight/detail?id=2664058878","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664058878?lang=en_us&edition=fundamental","pubTime":"2026-09-03 17:28","pubTimestamp":1788427680,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/RARE/analyst-ratings","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1158732819","title":"Ultragenyx Pharmaceutical Shares Crash 45% After Angelman Syndrome Drug Trial Disappoints","url":"https://stock-news.laohu8.com/highlight/detail?id=1158732819","media":"Trading Random","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1158732819?lang=en_us&edition=fundamental","pubTime":"2026-09-03 16:42","pubTimestamp":1788424931,"startTime":"0","endTime":"0","summary":"Shares of $Ultragenyx Pharmaceutical(RARE)$ plummeted 45%. The sharp decline came after the company revealed that its Phase 3 Aspire study evaluating apazunersen for Angelman syndrome did not meet...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Ultragenyx Pharmaceutical Shares Crash After Angelman Syndrome Drug Trial Disappoints","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664826205","title":"Ultragenyx Pharmaceutical Inc. : Baird Cuts to Neutral Rating; Cuts Target Price to $16 from $40","url":"https://stock-news.laohu8.com/highlight/detail?id=2664826205","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664826205?lang=en_us&edition=fundamental","pubTime":"2026-09-03 13:10","pubTimestamp":1788412211,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260903:nFWN44V06N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664825412","title":"Ultragenyx Pharmaceutical Inc. : TD Cowen Cuts Target Price to $18 from $49","url":"https://stock-news.laohu8.com/highlight/detail?id=2664825412","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664825412?lang=en_us&edition=fundamental","pubTime":"2026-09-03 11:51","pubTimestamp":1788407489,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260903:nFWN44U0ZM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664823007","title":"Ultragenyx Pharmaceutical Inc. : Canaccord Genuity Cuts Target Price to $37 from $83","url":"https://stock-news.laohu8.com/highlight/detail?id=2664823007","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664823007?lang=en_us&edition=fundamental","pubTime":"2026-09-03 11:21","pubTimestamp":1788405680,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260903:nFWN44U0WM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664847409","title":"Ultragenyx downgraded to In Line from Outperform at Evercore ISI","url":"https://stock-news.laohu8.com/highlight/detail?id=2664847409","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664847409?lang=en_us&edition=fundamental","pubTime":"2026-09-03 08:30","pubTimestamp":1788395409,"startTime":"0","endTime":"0","summary":"Evercore ISI downgraded Ultragenyx (RARE) to In Line from Outperform with a price target of $16, down from $34. Angelman syndrome is a huge unmet n...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-downgraded-to-in-line-from-outperform-at-evercore-isi-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-downgraded-to-in-line-from-outperform-at-evercore-isi-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664257847","title":"Evercore ISI downgrades Ultragenyx Pharmaceutical (RARE) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2664257847","media":"TIPRANKS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664257847?lang=en_us&edition=fundamental","pubTime":"2026-09-03 08:25","pubTimestamp":1788395122,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical received a Hold rating and price target from Evercore ISI analyst Gavin Clark-Gartner yesterday. According to TipRanks, C...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/evercore-isi-downgrades-ultragenyx-pharmaceutical-rare-to-a-hold-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/evercore-isi-downgrades-ultragenyx-pharmaceutical-rare-to-a-hold-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664407847","title":"Ultragenyx downgraded to Market Perform from Outperform at William Blair","url":"https://stock-news.laohu8.com/highlight/detail?id=2664407847","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664407847?lang=en_us&edition=fundamental","pubTime":"2026-09-03 08:20","pubTimestamp":1788394809,"startTime":"0","endTime":"0","summary":"William Blair downgraded Ultragenyx (RARE) to Market Perform from Outperform. The firm notes that it is disappointed the Phase 3 Angelman syndrome ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-downgraded-to-market-perform-from-outperform-at-william-blair-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-downgraded-to-market-perform-from-outperform-at-william-blair-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664449248","title":"William Blair downgrades Ultragenyx Pharmaceutical (RARE) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2664449248","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664449248?lang=en_us&edition=fundamental","pubTime":"2026-09-03 06:05","pubTimestamp":1788386726,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical received a Hold rating and price target from William Blair analyst Sami Corwin today. According to TipRanks, Corwin is a ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/william-blair-downgrades-ultragenyx-pharmaceutical-rare-to-a-hold-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/william-blair-downgrades-ultragenyx-pharmaceutical-rare-to-a-hold-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664841022","title":"Ultragenyx Says Phase 3 Study on Rare Neurogenetic Disorder Missed Primary, Secondary Endpoints; Shares Fall After-Hours","url":"https://stock-news.laohu8.com/highlight/detail?id=2664841022","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664841022?lang=en_us&edition=fundamental","pubTime":"2026-09-03 05:20","pubTimestamp":1788384025,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical  said late Wednesday the phase 3 Aspire study of apazunersen in Angelman syndrome, a rare, neurogenetic disorder, did not achieve its primary endpoint or its key secondary endpoint.The late-stage study did not reach the primary endpoint of change from Baseline in Bayley-4 cognitive raw score nor the key secondary endpoint of net response in Multidomain Responder Index, according to a statement.The safety profile for the phase 3 trial remained consistent with phase 1 and phase 2, the company said.Ultragenyx said it will assess the apazunersen program following this outcome and make a decision on its disposition.Shares of Ultragenyx were down about 45% in after-hours trading.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664417628","title":"Ultragenyx Pharmaceutical to Cut Costs After Drug Trial Misses Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2664417628","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664417628?lang=en_us&edition=fundamental","pubTime":"2026-09-03 05:13","pubTimestamp":1788383580,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical said it will look to reduce expenses and evaluate its development of apazunersen after the drug failed to meet its primary endpoint in a Phase 3 trial.The treatment didn't meet the primary endpoint of improving cognitive scores in patients with Angelman syndrome, a rare neuro-genetic disease, the company said. The drug also missed the study's secondary endpoint.Based on the results, Ultragenyx said it will evaluate the apazunersen program and make a decision on its future. It said it will also \"assess its planned operations to define and implement significant expense reductions, while supporting its growing commercial business.\"Shares plunged on the news, trading down 45% at $14.65 after Wednesday's bell.\"Based on everything we observed in the robust Phase 1/2 clinical development program and long-term extension study, we are disappointed by the Aspire result,\" Chief Executive Emil Kakkis said.He added that the company will focus on expanding its existing comm","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664849589","title":"Ultragenyx's Rare Disease Drug Fails in Late-Stage Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2664849589","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664849589?lang=en_us&edition=fundamental","pubTime":"2026-09-03 04:06","pubTimestamp":1788379565,"startTime":"0","endTime":"0","summary":"Ultragenyx's rare disease drug fails in late-stage trialSept 2 (Reuters)-Ultragenyx PharmaceuticalRARE.Osaid on Wednesday its experimental drug for a rare genetic neurodevelopmental disorder did not meet the main goal in a late-stage trial.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260902:nL4N44U1TA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":9,"pageCount":3,"totalSize":172,"code":"91000000","status":"200"}]}}